Running back Ryan Mathews is officially questionable for Monday night's showdown with the New York Giants due to the groin injury that limited him during Friday's practice.

Four players are out for the Eagles: wide receiver Nelson Agholor (ankle), linebacker Kiko Alonso (knee), defensive end Brandon Bair (groin) and linebacker Mychal Kendricks (hamstring).

Wide receiver Josh Huff, who is coming off the best game of his career in the win over the Saints, will start on the outside in Agholor's place. Rookie linebacker Jordan Hicks will start alongside DeMeco Ryans in the 3-4 base package with Alonso and Kendricks out.

WR Beckham Questionable For Giants

The Giants have listed wide receiver Odell Beckham Jr. as questionable for Monday night with a hamstring injury. He did not practice on Thursday or Friday. Giants head coach Tom Coughlin told reporters that Saturday would be a recovery day before a walkthrough on Sunday.

New York will be without three starters in cornerback Prince Amukamara (pectoral), wide receiver Victor Cruz (knee) and linebacker Devon Kennard (hamstring). Jayron Hosley is slated to start at cornerback, while Mark Herzlich started for Kennard last Sunday against the 49ers. Former Cowboy Dwayne Harris has been the slot receiver in Cruz's absence.

Those aren't the only injuries the Giants are dealing with on defense. Starting defensive end Robert Ayers (hamstring) is questionable after being limited during the team's two main practices. Starting middle linebacker Jon Beason is questionable after suffering a concussion last week against San Francisco. Cornerback Trumaine McBride, who is expected to work out of the slot, is questionable with a groin injury that kept him out of Friday's practice. Linebacker Jonathan Casillas is questionable with a calf injury.

Wide receiver Rueben Randle (hamstring) and defensive end George Selvie (calf) are probable for the Giants.

Check out the full injury report here.